Women Biochemists

American biochemist Jennifer Doudna of the University of California, Berkeley, who has made fundamental contributions in biochemistry and genetics, is best-known for her pioneering work in CRISPR gene-editing. Doudna and Emmanuelle Charpentier received the 2020 Nobel Prize in Chemistry for developing a method for genome editing through CRISPR, marking them as the only two women to share science Nobel ever.

The first woman to command the International Space Station, NASA astronaut Peggy Whitson was born to farmers and decided to become an astronaut after watching the moon landing on TV. She also boasts of a PhD in biochemistry and has been a researcher and educator of biochemistry and genetic engineering.

Dorothy Hodgkin received the 1964 Nobel Prize for mapping the structure of penicillin and Vitamin B12. She is also known for her work on insulin. Beginning her work on structure of an organic compound by using X-ray crystallography as an undergraduate student, she later developed it further and used it to determine the three-dimensional structure of complex organic molecules.

The daughter of Jewish immigrants in New York, Gertrude B. Elion excelled in chemistry at Hunter College, where she studied for free, but was initially unable to find a job due to gender bias. The renowned biochemist and pharmacologist later won a Nobel and became a pioneer in medical research.

Austro-Hungarian-American biochemist Gerty Cori is best-known for discovering the course of catalytic conversion of glycogen with her husband Carl Ferdinand Cori for which they jointly won the 1947 Nobel Prize in Physiology or Medicine. With this Gerty became the third woman to win a Nobel in science and the first to win it in this category.

Hungarian biochemist Katalin Karikó is best known for her research on mRNA, which led scientists to develop the first mRNA-based vaccine in the wake of the COVID-19 pandemic. After working at the Biological Research Centre in Szeged, she moved to the US due to lack of funding.

Marie Maynard Daly was the first Black lady to earn a doctoral degree in chemistry in the U.S. She was inspired by her father, who had to drop out of Cornell due to lack of funds. A pioneer of biochemistry, Daly later introduced a scholarship for African-American students at Queens College.

Shannon Lucid once held the record for the longest space stay by any woman and by any American. Born in China, to missionaries, she was imprisoned by the Japanese, along with her parents, as an infant. The family then moved to the U.S., where Lucid studied at the University of Oklahoma.

Shirley Marie Tilghman, the nineteenth President of Princeton University, currently the Emeritus Professor of Molecular Biology and Public Affairs, is considered to be one of the most influential female scientists of our time. Although she is no longer involved in active research she is known for her contributions in the fields of molecular genetics, especially in genomic imprinting.

German biochemist and pharmacist Johanna Budwig is best remembered for her anti-cancer diet known as the Budwig diet. Her extensive research on fatty acids helped her create the diet that consists of flaxseed oil, cottage cheese, and low-fat milk. However, there’s no scientific evidence that proves the effectiveness of the diet.

Carol W. Greider is a molecular biologist who discovered the enzyme telomerase in 1984. Her discovery was honored several years later when she received the 2009 Nobel Prize for Physiology or Medicine, along with Blackburn and Jack W. Szostak for their work on telomeres.  The trio also shared the Albert Lasker Award for Basic Medical Research for the same work.  

Margarita Salas was a Spanish scientist, author, and medical researcher. She is best remembered for her work in the fields of molecular genetics and biochemistry. In 2016, Margarita Salas became the first woman to be honored with the Echegaray medal. She was also the first woman from scientific background to become a member of the Royal Spanish Academy.

Maud Menten was a Canadian bio-medical and medical researcher. She made several important contributions to enzyme kinetics and histochemistry. She studied medicine at the University of Toronto, becoming among the first women in Canada to earn a medical doctorate. She collaborated with Leonor Michaelis to come up with the Michaelis-Menten equation model.

Apart from facing discrimination as a Russian Jew, Mildred Cohn also battled gender bias, being denied a promotion at NACA for being the only woman among the 70 staff members. Her pioneering use of NMR in the study of enzyme reactions later earned her a National Medal of Science.

Florence B. Seibert is remembered for developing the tuberculin test, which became the standard test for detecting TB. Defeating polio at age 3, she went on to win scholarships and made it to Yale. One of the greatest women biochemists of the U.S., she also contributed to intravenous drug therapy.

British-American mathematician and biochemist Dorothy Maud Wrinch initially gained recognition as the only female wrangler of the Mathematical Tripos in 1916. She later taught math at the universities of Oxford and Cambridge and became the first woman in the world to get a doctorate in science from Oxford.

Muriel Wheldale Onslow was a British biochemist. She is best remembered for her work concerning the biochemistry of anthocyanin pigment molecules. Wheldale Onslow was also one of the first women to be appointed as a lecturer at Cambridge.

Better known as Hamilton star Lin-Manuel Miranda's wife, Vanessa Nadal is a lawyer and teaches at the Fordham Law School. She also boasts of a chemical engineering degree from MIT and has worked at Johnson & Johnson. Vanessa and Lin-Manuel were in high school together, which is where their love blossomed.